2025-02-25

Discoveries by a German research team pave the way for new opportunities for individuals suffering from autoimmune diseases.

Wellness
Discoveries by a German research team pave the way for new opportunities for individuals suffering from autoimmune diseases.
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Preliminary findings indicate that CAR-T therapy may serve as a potent method for addressing and potentially overcoming certain medical conditions.

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Janina Paech, a medical student and lupus patient who underwent CAR-T therapy, is seen in a park close to her clinic. Photo by Ksenia Kuleshova for STAT.

ERLANGEN, Germany — In 2021, scientists in Germany made a remarkable announcement. They had successfully induced remission in a young woman suffering from severe lupus, a condition that was causing her organs to fail, by using an innovative treatment method.

Similar to other autoimmune disorders, where the immune system erroneously targets the body, lupus is a long-lasting condition that doesn’t just vanish. For patients, the most promising approach is to manage their symptoms through consistent use of medication. However, this 20-year-old woman experienced a remarkable turn of events; her illness seemed to disappear entirely, leading her to discontinue her other treatments. 

It was just a single case report, and in any case the team wasn’t well-known in the global lupus research world. The paper didn’t gain much traction. 

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